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Date: Oct 01, 2020

Humboldt Fellowship for Dr. Sophie Hendrix - How plants resist heat Ferroptosis is a form of cell death that depends on iron and the accumulation of lipid hydroperoxides and has been well characterized in human tumour cells.

Recently, ferroptosis-like cell death was also demonstrated in Arabidopsis thaliana plants subjected to heat stress. Nevertheless, the molecular mechanisms underlying ferroptosis in plants remain elusive. The main goal of my project is to further characterize two membrane-localized glutathione peroxidase-like proteins and investigate their involvement in detoxifying lipid peroxidation products and preventing ferroptosis. The fundamental knowledge obtained in this project can significantly contribute to the development of strategies to improve plant growth under heat stress, which is of crucial importance in the context of global warming.
Sophie Hendrix is 29 years old and was born in Belgium. In 2013, she graduated with great distinction from the transnational University Limburg as a master in Biomedical Sciences with a specialisation in Environmental Health Sciences. In 2019, she obtained a PhD in Biology from Hasselt University (Belgium). During her PhD research in the Environmental Biology research group of Prof. Dr. Ann Cuypers, Sophie investigated the involvement of the antioxidative metabolite glutathione and the transcription factor Suppressor of Gamma Response 1 (SOG1) in plant responses to cadmium stress. Since June 2019, she has been working as a postdoctoral researcher at Hasselt University. Recently, Sophie has been awarded a prestigious Humboldt Fellowship to continue her work as a postdoctoral fellow from October 1 onwards in the Chemical Signalling lab in Bonn.

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