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SUMMARY:Plant Science Colloquium with Prof. Dr. Saravanan Matheshwaran
DTSTART;TZID=Europe/Berlin:20241007T101500
DTEND;TZID=Europe/Berlin:20241007T111500
DTSTAMP:20260526T054159Z
UID:351b5f5853f44cbcbf3f3014ceaab392@www.inres.uni-bonn.de
CREATED:20240522T123141Z
DESCRIPTION:Ustilago maydis\, the fungus responsible for smut disease in m
 aize\, utilizes secondary metabolites like melanin to enhance its virulenc
 e and survival. Our research focuses on SWR1\, an ATP-dependent chromatin 
 remodeler\, and its role in melanin biosynthesis. We found that SWR1 alter
 s chromatin architecture\, affecting DNA activities. Deleting SWR1increase
 d U. maydis' sensitivity to DNA damage\, reduced growth\, and changed cell
  morphology. Even under optimal conditions\, the loss of SWR1 led to pigme
 nt production\, highlighting its regulatory role. Mating experiments in ma
 ize seedlings showed that the Δswr1 mutant had reduced infection rates an
 d caused chlorosis\, emphasizing SWR1's importance in virulence. This stud
 y highlights the role of chromatin remodeling in fungal adaptation and pat
 hogenicity\, offering new insights into combating crop diseases.
LAST-MODIFIED:20241002T090617Z
URL:https://www.inres.uni-bonn.de/en/about/events/pflanzenwissenschaftlich
 es-kolloquium-matheshwaran
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